In vitro expansion of mesenchymal stem cells for clinical use

168

In vitro expansion of mesenchymal stem cells for clinical use

Phuc Van Pham, Ngoc Bich Vu

 

Abstract

Mesenchymal stem cells (MSCs) now are popular stem cells for clinical applications. To date, MSCs were accepted in various disease treatments with several FDA approved treatments in some countries. One important requirement for the clinical usage of stem cells is the production of stem cells. Actually, the treatment efficacy of MSC transplantation depends on the quality of transplanted MSCs. This review aimed to present some guidelines for MSC production according to good manufacturing practice that helps to maintain the quality of stem cells from batch to batch as well as the clinical satisfaction.

Keywords

 

Good manufacturing practice, Mesenchymal stem cells, Clinical application, Stem cell therapy.